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Cake day: June 12th, 2023

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  • Yes. But if you have many complaints from MANY MANY users, it may not mean anything serious, it could still mean a very small fraction have problems. Absolute number means very little without context. That’s the purpose of the previous comment. Please note how it doesn’t say anything about qualities of Windows.



  • lemming@sh.itjust.workstoScience Memes@mander.xyzBubble Wrap!
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    2 months ago

    It isn’t great when a doctor goes to fetch their colleague to have a look while examinig you. But of course that after all the same boring stuff, they are excited about something unusual. I heard about an ophthalmologist who, out of all her carreer, was most excited about solving someone’s issues by finding crabs in their eyebrows.










  • It has a part that is embedded in a mitochondrial membrane and works as a rotor. The other part is sticking out from the membrane and is responsible for synthesis of ATP from ADP and phosphate. An off-axis part of the rotor pushes the stator, it changes shape and pushes ADP and phosphate together, until they fuse to ATP.

    To make the rotor move, it makes use of membrane potential. One side of the membrane has a lot more H⁺ (just protons, really) than the other. The excess H⁺ want to go to the other side. The membrane doesn’t let them through. It is hydrophobic on the inside, so it does’t let through anything charged (like H⁺) or polar (like water). This is the potential and it has quite a lot of energy. ATP synthase lets the H⁺ through by binding them to the rotor in the membrane in a particular place and releases them in another in such a way that forces the rotor to turn almost a full turn before they can leave and stops it from rotating the other way. As mentioned, the rotation is transfered to the stator, changing its shape and thus creating ATP. As a side note, multiple H⁺ are bound on the rotor along its circumference, so each rotation is powered by the potential energy of multiple protons.

    Of course, it’s a bit more complicated than that, but I don’t think there’s anything downright wrong or misleading in what I wrote. I hope I managed to make it understandable. Also, I recommend animations of the synthase on youtube.